Fig 1: Plasma EPO (A), ERFE (B) and Ft (C) concentrations in iron dextran-loaded BKO mice treated with DI, GTE (50 mg EGCG equivalent/kg), DFP (50 mg/kg) and GTE (50 mg EGCG equivalent/kg) in conjunction with DFP (50 mg/kg) for a period of 2 months. Data are expressed as mean ± SEM values. Accordingly, ** p < 0.01 when compared with DI. Abbreviations: BKO = ß-globin gene knockout, DFP = deferiprone, DI = deionized water, EGCG = epigallocatechin 3-gallate, EPO = erythropoietin, ERFE = erythroferrone, GTE = green tea extract, SEM = standard error of the mean.
Fig 2: Herein, mRNA levels of Epo (A) and Erfe (B) taken from kidney and spleen tissues, respectively that had been collected from iron dextran-loaded BKO mice treated with DI, GTE (50 mg EGCG equivalent/kg), DFP (50 mg/kg) and GTE (50 mg EGCG equivalent/kg) in conjunction with DFP (50 mg/kg) for a period of 2 months. Data are expressed as mean ± SEM values. Accordingly, * p < .05 when compared with DI. Abbreviations: BKO = ß-globin gene knockout, DFP = deferiprone, DI = deionized water, EGCG = epigallocatechin 3-gallate, Epo = erythropoietin gene, Erfe = erythroferrone gene, GTE = green tea extract, SEM = standard error of the mean.
Supplier Page from Abbexa Ltd for Mouse Erythroferrone (ERFE) ELISA Kit